CBD oil or cannabidiol has a proven edge in the world of natural medicine. However, its drug interaction on some notable medications should also be noted. CBD oil has the most significant drug interaction effect on anxiety medications, blood thinners, and pain relievers. Let’s find out below how CBD oil interacts with these medications and what are the effects.

CBD oil’s impact on anxiety medication

The popular medications for anxiety are Xanax and Ativan. Experts say that the simultaneous intake of CBD oil and any of these medications could potentially increase the latter’s side effects (Ries, 2019). How? CBD oil could potentially block the metabolism of the compounds found in anti-anxiety drugs. If the metabolism of anti-anxiety drugs is not fully realized, it could intensify some side effects like drowsiness, sedation, and more.

CBD oil’s impact on blood thinners

Experts say that the utilization of CBD oil with blood thinners might not be a good idea (Carrie ND). CBD can block the full metabolism (or the breaking down of the substance into molecules for cell absorption) of blood thinners. If the blood-thinning medication is not metabolized well, its amount in your body system increases. The increase in the amount of blood thinners could render some adverse effects on the body. Some of these adverse effects are traumatic bleeding or hemorrhage.

CBD oil’s impact on pain relievers

Unfortunately, CBD oil could also negatively affect pain relievers like antibiotics, Advil, Aleve, and more. This is because CBD oil could potentially alter how these drugs behave in our bodies. And we all know, when drugs aren’t processed well in the body, it intensifies its inherent side effects.

Final Thoughts

The intensity of CBD oil’s effects on the mentioned medication is simply controlled by the dosage of both the drug and CBD oil. For example, if CBD oil’s concentration is high, it could possibly affect how the drugs behave in your system. On the other hand, if CBD oil has a lower concentration, it could not possibly affect the drugs taken in our system.

Timing is also crucial in controlling the drug interaction between CBD oil and these types of drugs (Ries, 2019). The longer the time of space between the intake of CBD oil and the drugs, the little the percentage of a drug interaction. This is because you are giving your liver a breather from the exhausting metabolism process of drugs.

One can conclude that patients who take anxiety and blood thinning drugs should stay away from CBD oil. If you really want to mix CBD oil with these kinds of medication, kindly advise your doctor first. He could adjust the dosage of these types of medications for you.

The bottom line is, regardless of CBD oil’s effect on these medications, it is important to consult your doctor about taking both CBD oil and the mentioned medications simultaneously. But altogether, don’t be afraid of the idea about trying CBD oil.



Ries, Julia (2019) CBD May Possibly Interfere With Your Daily Medication. Available at:

Carrie (N.D) Drugs that May Interact with CBD Oil. Available at: