In this article, we’ll look at a study titled “A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. ” This study led by Khalid Jadoon details the effects of CBD on certain physiological parameters such as heart rate, body temperature, and blood pressure. Before we delve into this 2017 study, let’s do a review first on CBD.
What is CBD?
CBD or cannabidiol is a phyto compound found in the cannabis plant. The cannabis genus branches out to hemp and marijuana. Although different strains yield different CBD content, industrial hemp is mostly known for its abundance of CBD.
Unlike its sibling cannabinoid, THC (tetrahydrocannabinol), CBD is non-psychoactive, meaning, it can’t get you high. Because of CBD’s non-psychoactive nature, the medical world has shifted its explorations from THC to CBD. True enough, CBD didn’t disappoint. It turns out, CBD has so much to offer.
One of CBD’s therapeutic effects concerns high blood pressure. Since CBD has an innate ability to soothe inflammation, researchers see CBD as a potential cure for heart conditions such as high blood pressure.
“A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study”
In this study by Jadoon, Tan, and O’Sullivan, they reported that a single dose of CBD successfully reduced the blood pressure of healthy volunteers. Although it’s not certain whether these volunteers have had a heart condition, it’s still encouraging to know that in some way, CBD can reduce blood pressure. Let’s look at some of the effects of CBD on the physiological parameters tested on the study.
In a resting state, under a single CBD dose, the volunteers experienced increased heart rate but maintained their cardiac output. Moreover, before and after the external factor “stress” is introduced to the volunteers, under CBD, they also experienced an increased heart rate. Finally, during a series of cold stress, under CBD single-dose treatment, the volunteers, once again, experienced an increased heart rate.
The study didn’t think “body temperature” has a significance in their effort to document the effect of CBD on blood pressure. Therefore, they didn’t bother to record the volunteers’ body temperature during their series of tests. However, the subjects’ certain body parts such as the feet were treated on cold conditions by 4°C–6°C.
The blood pressure parameter is maybe the most important cardiac parameter they’ve ever analyzed in this study because it aptly showed that under several circumstances, CBD-treated individuals get their blood pressure reduced by a significant number.
In a resting state, under a single CBD dose, the volunteers experienced reduced systolic BP (–6 mmHg; P < 0.05) and stroke volume (–8 ml; P < 0.05). Moreover, before and after the external factor “stress” is introduced to the volunteers, under CBD, volunteers had a lower BP of –5 mmHg; P < 0.05. In response to cold stress, subjects who had taken CBD also had lowered blood pressure at –6 mmHg; P < 0.01.
The data collected from the study shows that the acute administration of CBD on healthy individuals can reduce blood pressure and temporarily increase heart rate. In the end, the study called for further studies to establish the potential therapeutic effects of CBD on cardiovascular disorders.